Literature summary for 2.1.1.137 extracted from

Maimaitiyiming, Y.; Wang, C.; Xu, S.; Islam, K.; Chen, Y.J.; Yang, C.; Wang, Q.Q.; Naranmandura, H.
Role of arsenic (+3 oxidation state) methyltransferase in arsenic mediated APL treatment an in vitro investigation (2018), Metallomics, 10, 828-837 .

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Application

Application	Comment	Organism
medicine	the proliferation of NB4 cells is significantly inhibited in a transwell system cocultured with AS3MT-transfected HepG2 cells after exposure to arsenite. The therapeutic efficacy of As2O3 (i.e., iAsIII) in acute promyelocytic leukemia patients is probably associated with the production of methylated arsenic metabolites by AS3MT	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9HBK9	-	-

Synonyms

Synonyms	Comment	Organism
AS3MT	-	Homo sapiens

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Release 2023.1 (January 2023)